For patients, a story about their medicines, omeprazol (Losec®) and other drugs, how they were created and how they work. For researchers in industry, a challenge to create new ones. The collaboration with basic research and the fighting spirit demonstrated in the projects are presented as "a Swedish model".
Drugs of Natural Origin is a unique multidisciplinary book suitable for undergraduate
and graduate students and teachers in the area of natural product science, but also as a
complementary book for disciplines like medicinal chemistry, biochemistry and pharmacology.
The book can also serve society as a scientific source for the understanding of a sustainable
use of natural products in the development of new drugs, scientifically based herbal remedies,
and environmentally friendly biomolecules.
This is the story of some discoveries that led to modern medicine and about the pioneers who through their keen observations, pure chance, sudden strokes of luck and dedicated hard work made them possible.
Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications teaches everyday biological data analysis to the undergraduate and graduate levels. Through numerous examples and over 100 tutorials, scientists learn how to use PK/PD seamlessly in a variety of practical areas, from simple plasma kinetics, multi-compartment models, nonlinear kinetics, plasma protein binding, pharmacodynamic models, turnover concepts, receptor binding, functional adaption and rebound, dose-response-time data analysis, inter-species scaling and a lot more. Price includes worldwide shipping!
PKPD awareness is vital if we are to attempt to relate preclinical results to the acute and long term consequences in humans. The debate on whether preclinical findings can be translated to the human usage is still engaging scientists across industry, academia and regulatory bodies.